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ATX inhibitor 22

ATX Inhibitor

ATX Inhibitor 22 is a selective inhibitor of autotaxin (ATX), demonstrating an IC50 of 218 nM. This compound effectively blocks ATX activity, which is significant in lysophosphatidate signaling pathways. Due to its mechanism of action, it is valuable for research applications focused on cell migration, cancer metastasis, and various inflammatory conditions, though it does not inhibit LPAR1.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2969213-59-8
Applications	ATX Inhibitor
Formula	C₁₉H₁₇Cl₃F₂N₂O₄S
Molecular Weight	513.77
SMILES	CS(=O)(N(C1CCOCC1)C2=C(C=C(C(C(NC3=CC(F)=C(C(F)=C3)Cl)=O)=C2)Cl)Cl)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.