Documents & Downloads

ATX inhibitor 25

Autotaxin Inhibitor

ATX Inhibitor 25 is a potent autotaxin inhibitor, demonstrating an IC50 of 1.08 nM. This compound exhibits high metabolic stability in vitro, with a half-life exceeding 170 minutes. In preclinical studies, ATX Inhibitor 25 has been shown to exert anti-fibrotic effects in a bleomycin-induced pulmonary fibrosis mouse model, highlighting its potential for therapeutic applications in fibrotic diseases.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2951100-44-8
Applications	Autotaxin Inhibitor
Formula	C₂₃H₂₀ClFN₄O₅
Molecular Weight	486.88
SMILES	CC1=C(C(NC2=CC(C(O)=O)=C(F)C=C2)=O)C3=CC(OC)=C(Cl)C=C3N1C4=CN(COC)N=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.