Documents & Downloads

ATX inhibitor 26

ATX Inhibitor

ATX Inhibitor 26 is a potent Autotaxin (ATX) inhibitor, exhibiting an IC50 of 57 nM in human plasma. This compound effectively inhibits cell migration and collagen gel contraction, demonstrating significant anti-fibrotic activity. Notably, ATX Inhibitor 26 reduces collagen deposition in models of pulmonary fibrosis induced by Bleomycin, making it a valuable tool for research into fibrosis-related processes and therapeutic interventions.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2940248-11-1
Applications	ATX Inhibitor
Formula	C₁₈H₁₉Cl₂N₇O₃
Molecular Weight	452.29
SMILES	ClC1=CC(Cl)=CC(COC(N2CCC(C3=NN=C(NCC4=CN=NN4)O3)CC2)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.