Documents & Downloads

ATX inhibitor 27

ATX Inhibitor

ATX Inhibitor 27 is a potent inhibitor of autotaxin (ATX) with an IC50 of 13 nM against human ATX and 23 nM against lysophosphatidylcholine (LPC). By effectively reducing lysophosphatidic acid (LPA) levels in vivo, ATX Inhibitor 27 serves as a valuable tool in researching ATX-LPA-related diseases, including inflammation, neurodegenerative disorders, and cancer. This compound is useful for studies aimed at understanding the role of ATX in various pathological conditions.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2023027-81-6
Applications	ATX Inhibitor
Formula	C₂₆H₂₆ClN₅O₃
Molecular Weight	491.97
SMILES	CC(N1CCC(C2=CC3=C(N=CN(CC(N(C)CC4=CC=C(C#N)C(Cl)=C4)=O)C3=O)C=C2)CC1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.