Fig. 1 · Structure

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ATX inhibitor 8

Autotaxin Inhibitor

ATX Inhibitor 8 is a selective inhibitor of Autotaxin (ATX), which plays a crucial role in the synthesis of lysophosphatidic acid (LPA). This compound exhibits significant biological activity by modulating ATX-mediated pathways, making it a valuable tool for research into cancer metastasis, fibrosis, and neurodegenerative disorders. Its targeted inhibition of ATX may provide insights into therapeutic strategies for diseases associated with elevated LPA levels.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2156656-37-8
Applications Autotaxin Inhibitor
Formula C28H26N10O
Molecular Weight 518.57
SMILES
O=C(N1CCC(N=NN2)=C2C1)CN3N=C(C4=CC=NC=C4)C(C5=CN=C(NC6CC7=C(C=CC=C7)C6)N=C5)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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