Fig. 1 · Structure

Documents & Downloads

AU1235

Mycobacterium tuberculosis

AU1235 is an adamantyl urea inhibitor of Mycobacterium tuberculosis.

In Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
Sf21 IC50 0.4 nM Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assay [PMID: 31488357]
Vero IC50 725.8 μg/mL Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay [PMID: 21840723]

Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1338780-86-1
Applications Mycobacterium tuberculosis
Formula C17H19F3N2O
Molecular Weight 324.34
SMILES
O=C(NC(C=CC(F)=C1F)=C1F)NC2(C[C@H](C3)C4)C[C@H]4C[C@H]3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 9 mg/mL (27.75 mM)
Water Insoluble
Ethanol 61 mg/mL (188.07 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Added to your cart

View Cart Checkout
Loading...