Fig. 1 · Structure
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AubipyOMe
Cat. No.
A71718
CAS
1221591-26-9
Endogenous Metabolite
AubipyOMe is a selective inhibitor of tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme implicated in osteoclast and macrophage activity. It exhibits IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b, effectively inhibiting TRAP activity in murine macrophage extracts and human lung tissue. This compound is valuable for studying bone resorption and macrophage function in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1221591-26-9 |
| Applications | Endogenous Metabolite |
| Formula | C12H12AuCl2F6N2O2P |
| Molecular Weight | 629.07 |
| SMILES | [F-][P+5]([F-])([F-])([F-])([F-])[F-].[Cl-][Au+3]1([N]2=CC=C(C=C2C3=[N]1C=CC(OC)=C3)OC)[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.