Auristatin E

Catalog No.: A21269

cytotoxic tubulin modifier

Auristatin E

Auristatin E Chemical Structure

CAS NO. 160800-57-7

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin.

Availability: In stock

Package Price Qty
1 mg
$198.00
5 mg
$594.00
10 mg
$1,012.00
50 mg
$3,036.00
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Biological Activity

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.66 mL 68.31 mL 136.61 mL
0.5 mM 2.73 mL 13.66 mL 27.32 mL
1 mM 1.37 mL 6.83 mL 13.66 mL
5 mM 0.27 mL 1.37 mL 2.73 mL

*The above data is based on the productmolecular weight 732.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21269
CAS No. 160800-57-7
Formula C40H69N5O7
M. Wt 732.01
Purity >98%
SMILES CC(C)[[email protected]](N(C)C)C(N[[email protected]](C(N([[email protected]@H]([[email protected]@H](C)CC)[[email protected]@H](CC(N1CCC[[email protected]@]1([H])[[email protected]](OC)[[email protected]@H](C)C(N[[email protected]](C)[[email protected]](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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