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$0.00 Biological Activity
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.66 mL | 68.31 mL | 136.61 mL |
| 0.5 mM | 2.73 mL | 13.66 mL | 27.32 mL |
| 1 mM | 1.37 mL | 6.83 mL | 13.66 mL |
| 5 mM | 0.27 mL | 1.37 mL | 2.73 mL |
*The above data is based on the productmolecular weight 732.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21269 |
|---|---|
| CAS No. | 160800-57-7 |
| Formula | C40H69N5O7 |
| M. Wt | 732.01 |
| Purity | >98% |
| SMILES | CC(C)[[email protected]](N(C)C)C(N[[email protected]](C(N([[email protected]@H]([[email protected]@H](C)CC)[[email protected]@H](CC(N1CCC[[email protected]@]1([H])[[email protected]](OC)[[email protected]@H](C)C(N[[email protected]](C)[[email protected]](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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