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AV-4025 hydrochloride

NS5A Inhibitor

AV-4025 hydrochloride is an orally active NS5A inhibitor, demonstrating potent antiviral activity against Hepatitis C Virus (HCV) replicon genotype 1b with an EC50 of 0.003 nM. This compound is valuable for research applications focused on the mechanisms of hepatitis C infection and the development of antiviral therapeutics.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1380290-35-6
Applications	NS5A Inhibitor
Formula	C₃₈H₄₈Cl₂N₈O₆
Molecular Weight	783.74
SMILES	O=C([C@@H](NC(OC)=O)C(C)C)N1CCC[C@H]1C(N2)=NC=C2C3=CC=C(C#CC#CC4=CN=C([C@H]5N(C([C@H](C(C)C)NC(OC)=O)=O)CCC5)N4)C=C3.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.