Avadomide (CC-122)

Name: Avadomide (CC-122)
Brand: Adooq Bioscience
SKU: A16854
Rating: 5 (288 reviews)

Catalog No.: A16854

E3 Ligase inhibitor

Avadomide(CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.

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Avadomide (CC-122) 1015474-32-4 E3 Ligase inhibitor

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Grouped product items
Size	Price	Stock
5mg	$25.00	In stock
10mg	$35.00	In stock
25mg	$75.00	In stock
50mg	$120.00	In stock
100mg	$190.00	In stock
200mg	$290.00	In stock
*10mM 1mL in DMSO**	$25.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	Avadomide(CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.

Product Information

Catalog Num	A16854
Formula	C14H14N4O3
Molecular Weight	286.29
CAS Number	1015474-32-4
SMILES	O=C(C(N1C(C)=NC2=C(C(N)=CC=C2)C1=O)CC3)NC3=O
Synonyms	CC122, CC 122
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	50 mg/mL (174.64 mM)
	Water	Insoluble
	Ethanol	<1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	34.93 mL	174.65 mL	349.3 mL
0.5 mM	6.99 mL	34.93 mL	69.86 mL
1 mM	3.49 mL	17.46 mL	34.93 mL
5 mM	0.7 mL	3.49 mL	6.99 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂