Avadomide (CC-122)

Catalog No.: A16854

E3 Ligase inhibitor

Avadomide (CC-122)

Avadomide (CC-122) Chemical Structure

CAS NO. 1015474-32-4

Avadomide(CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$175.00
50 mg
$445.00
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Biological Activity

Avadomide(CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.93 mL 174.65 mL 349.3 mL
0.5 mM 6.99 mL 34.93 mL 69.86 mL
1 mM 3.49 mL 17.46 mL 34.93 mL
5 mM 0.7 mL 3.49 mL 6.99 mL

*The above data is based on the productmolecular weight 286.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16854
Actions Inhibitor
M. Wt 286.29
Formula C14H14N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1015474-32-4
Synonyms CC122, CC 122
SMILES O=C(C(N1C(C)=NC2=C(C(N)=CC=C2)C1=O)CC3)NC3=O

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