Target & Activity
| Target | Activity | Value |
|---|---|---|
| PDE5 | 1 nM |
Fig. 1 · Structure
Documents & Downloads
Avanafil
Cat. No.
A12619
CAS
330784-47-9
PDE5 inhibitor
Avanafil is a PDE5 Inhibitor for the Treatment of Erectile Dysfunction
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 330784-47-9 |
| Applications | PDE5 inhibitor |
| Formula | C23H26ClN7O3 |
| Molecular Weight | 483.95 |
| Synonyms | TA 1790 |
| SMILES | COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | 84 mg/mL (173.57 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.