Fig. 1 · Structure
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Avenciguat
sGC Activator
Avenciguat is a potent and orally active soluble guanylate cyclase (sGC) activator. By enhancing the production of cyclic guanosine monophosphate (cGMP), Avenciguat effectively improves nitric oxide (NO) signaling pathways. This compound is valuable for research on chronic kidney disease (CKD) and diabetic kidney disease (DKD), offering insights into therapeutic mechanisms and potential treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1579514-06-9 |
| Applications | sGC Activator |
| Formula | C34H38N4O5 |
| Molecular Weight | 582.69 |
| Synonyms | BI-685509 |
| SMILES | O=C(C1=C(OCC)N(C2=NC(C3=C(OCC4=CC=C5C(CCN(C6CCOCC6)C5)=C4C)C(C)=CC=C3)=CC=C2)N=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.