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AVI-4206

Mac1Inhibitor

AVI-4206 is a selective Mac1 inhibitor with an IC50 of 64 nM. This compound effectively reduces viral replication and restores the interferon response, demonstrating a survival benefit in animal models of SARS-CoV-2 infection. AVI-4206 is valuable for research applications focused on understanding SARS-CoV-2 mechanisms and potentially developing therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3105041-48-0
Applications	Mac1Inhibitor
Formula	C₁₉H₂₃N₇O₂
Molecular Weight	381.43
SMILES	O=C(NCC)NC1=CC=CC2=C1NC3=NC=NC(NN4C(C)(C)CCC4=O)=C32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.