Fig. 1 · Structure

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AVI-6451

Antiviral Agent

AVI-6451 is an orally effective antiviral agent targeting the SARS-CoV-2 Mac1 protein, exhibiting an IC50 of 28 nM. This compound effectively reduces viral load, making it a valuable tool for research on viral infections and related therapeutic approaches. Its mechanism of action supports investigations into the inhibition of SARS-CoV-2 replication and the development of antiviral strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3105043-06-6
Applications Antiviral Agent
Formula C18H18FN5O2
Molecular Weight 355.37
SMILES
O=C1OCC(C)(C)N1NC2=C3C(NC4=C3C=C(F)C=C4C5CC5)=NC=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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