Fig. 1 · Structure

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Avibactam sodium hydrate

Cat. No. A46332 CAS 2938989-90-1

Beta-lactamase Inhibitor

Avibactam sodium hydrate is a reversible non-β-lactam β-lactamase inhibitor that specifically targets β-lactamase enzymes TEM-1 and CTX-M-15, demonstrating IC50 values of 8 nM and 5 nM, respectively. This compound is crucial for enhancing the efficacy of β-lactam antibiotics against resistant bacterial strains. Its use in research applications includes investigations into antibiotic resistance mechanisms and the development of combination therapies to overcome β-lactamase-mediated resistance.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2938989-90-1
Applications Beta-lactamase Inhibitor
Formula C7H12N3NaO7S
Molecular Weight 305.24
Synonyms NXL-104 hydrate
SMILES
O=S(ON1[C@]2([H])CC[C@@H](C(N)=O)[N@@](C2)C1=O)(O[Na])=O.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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