AX-024 hydrochloride
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases. | ||
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Catalog Num | A18332 |
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Formula | C21H23ClFNO2 |
Molecular Weight | 375.8684 |
CAS Number | 1704801-24-0 |
SMILES | COC1=CC(C(C2=CC=C(F)C=C2)=C(CN3CCCC3)CO4)=C4C=C1.[H]Cl |
Synonyms | AX-024; AX 024; AX024 HCl; AX-024 hydrochloride |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 64 mg/mL (170.27 mM) | |
Water | 3 mg/mL (7.98 mM) | ||
Ethanol | 15 mg/mL (39.91 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.61 mL | 133.03 mL | 266.05 mL |
0.5 mM | 5.32 mL | 26.61 mL | 53.21 mL |
1 mM | 2.66 mL | 13.3 mL | 26.61 mL |
5 mM | 0.53 mL | 2.66 mL | 5.32 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2