AX-024 hydrochloride

Catalog No.: A18332

TNF receptor inhibitor

AX-024 hydrochloride

AX-024 hydrochloride Chemical Structure

CAS NO. 1704801-24-0

AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases.

Availability: In stock

Package Price Qty
2 mg
$105.00
5 mg
$165.00
10 mg
$275.00
50 mg
$1,050.00
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Biological Activity

AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.61 mL 133.03 mL 266.05 mL
0.5 mM 5.32 mL 26.61 mL 53.21 mL
1 mM 2.66 mL 13.3 mL 26.61 mL
5 mM 0.53 mL 2.66 mL 5.32 mL

*The above data is based on the productmolecular weight 375.8684. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18332
Actions Inhibitor
M. Wt 375.8684
Formula C21H23ClFNO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1704801-24-0
Synonyms AX-024; AX 024; AX024 HCl; AX-024 hydrochloride
SMILES COC1=CC(C(C2=CC=C(F)C=C2)=C(CN3CCCC3)CO4)=C4C=C1.[H]Cl

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