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AY77

Catalog No.: A23887

PAR2 agonist
AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release.
AY77
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Product Name Price Stock Qty
AY77 1mg
$645.00
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AY77 5mg
$2,118.00
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Biological Activity
Discription AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release.
Product Information
Catalog Num A23887
Formula C21H32N4O4
Molecular Weight 404.5
CAS Number 1835734-92-3
Sequence {5-Isoxazolylcarbonyl-Cha}-{Chg}-NH2
Sequence shortening {5-Isoxazolylcarbonyl-Cha}-{Chg}-NH2
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GPCR/G Protein > Protease-Activated Receptors (PAR)
Peptides
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