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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15873 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 428.53 |
| Formula | C25H28N6O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1645286-75-4 |
| Synonyms | AZ-6102, AZ 6102 |
| SMILES | C[[email protected]]1CN(C2=NC=C(C3=CC=C(C4=NC(C(C=CN5C)=C5N4)=O)C=C3)C(C)=C2)C[[email protected]@H](C)N1 |
Description |
AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells. | ||||||||||
Targets |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.34 mL | 116.68 mL | 233.36mL |
| 0.5 mM | 4.67 mL | 23.34 mL | 46.67 mL |
| 1 mM | 2.33 mL | 11.67 mL | 23.34 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.67 mL |
*The above data is based on the productmolecular weight 428.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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