Azacyclohexane-O-cyclohexane-C-(OCH3)2

Catalog No.: A83734
PROTAC Linker
Azacyclohexane-O-cyclohexane-C-(OCH3)2 is a PROTAC linker designed for the synthesis of PROTAC LRRK2 Degrader-3. This compound acts as a potent degrader of LRRK2, demonstrating significant anti-neuroinflammatory effects. It is valuable in research applications aimed at elucidating the role of LRRK2 in neurodegenerative diseases and exploring targeted protein degradation strategies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAzacyclohexane-O-cyclohexane-C-(OCH3)2 is a PROTAC linker designed for the synthesis of PROTAC LRRK2 Degrader-3. This compound acts as a potent degrader of LRRK2, demonstrating significant anti-neuroinflammatory effects. It is valuable in research applications aimed at elucidating the role of LRRK2 in neurodegenerative diseases and exploring targeted protein degradation strategies.
Product Information
Catalog NumA83734
FormulaC14H27NO3
Molecular Weight257.37
CAS Number2839672-81-8
SMILESCOC(OC)[C@@H]1CC[C@@H](OC2CCNCC2)CC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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