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Fig. 1 · Structure
Cat. No.
B19156
CAS No.
143484-82-6
Formula
C22H26Cl3N3O2S
Mol. Weight
502.88

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Azalanstat dihydrochloride

Cat. No. B19156 CAS 143484-82-6

Heme Oxygenase/Lanosterol 14α-Demethylase Inhibitor

Azalanstat dihydrochloride is an inhibitor of heme oxygenase and lanosterol 14α-demethylase, demonstrating selective inhibitory activity against HO-1 (IC50 = 5.5 µM) and HO-2 (IC50 = 24.5 µM). This compound has been shown to reduce the maturation rate of rat oocytes and increase oocyte degeneration, as well as partially inhibit progesterone production in preovulatory follicles in rats. Its usage is pertinent in studies focused on reproductive biology and the biochemical pathways involving heme oxygenase and steroidogenesis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 143484-82-6
Applications Heme Oxygenase/Lanosterol 14α-Demethylase Inhibitor
Formula C22H26Cl3N3O2S
Molecular Weight 502.88
Synonyms RS-21607 dihydrochloride
SMILES
ClC(C=C1)=CC=C1CC[C@]2(O[C@@H](CO2)CSC3=CC=C(C=C3)N)CN4C=CN=C4.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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