AZD6244 (Selumetinib)

AZD6244 (Selumetinib) also known as Selumetinib, ARRY142886, AZD-6244 & ARRY-142886 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm.
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Size Price Stock Qty
25mg
$40.00
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50mg
$55.00
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100mg
$75.00
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200mg
$120.00
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250mg
$145.00
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500mg
$190.00
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1g
$290.00
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10mM * 1mL in DMSO
$64.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AZD6244 (Selumetinib) has been cited by 1 publications
  • Chia-Chi Chang, .et al. , Oncotarget, 2016, Jun 7; 7(23): 35270-35283 PMID: 27150057
  • Biological Activity
    Discription AZD6244 (Selumetinib) also known as Selumetinib, ARRY142886, AZD-6244 & ARRY-142886 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10257
    Formula C17H15BrClFN4O3
    Molecular Weight 457.7
    CAS Number 606143-52-6
    SMILES CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
    Synonyms ARRY-142886
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 80 mg/mL (174.79 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.85 mL 109.24 mL 218.48 mL
    0.5 mM 4.37 mL 21.85 mL 43.7 mL
    1 mM 2.18 mL 10.92 mL 21.85 mL
    5 mM 0.44 mL 2.18 mL 4.37 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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