AZD6244 (Selumetinib)

AZD6244 (Selumetinib) also known as Selumetinib, ARRY142886, AZD-6244 & ARRY-142886 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm.
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Product Name Price Stock Qty
AZD6244 100mg
$80.00
In stock
AZD6244 250mg
$150.00
In stock
AZD6244 500mg
$250.00
In stock
AZD6244 (Selumetinib) 10mM * 1mL in DMSO
$64.00
In stock
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Adooq Products cited in reputable paper
Adooq's AZD6244 (Selumetinib) has been cited by 1 publications
  • Chia-Chi Chang, .et al. , Oncotarget, 2016, Jun 7; 7(23): 35270-35283 PMID: 27150057
  • Biological Activity
    Discription AZD6244 (Selumetinib) also known as Selumetinib, ARRY142886, AZD-6244 & ARRY-142886 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm.
    Targets
    Target Value
    Product Information
    Catalog Num A10257
    Formula C17H15BrClFN4O3
    Molecular Weight 457.7
    CAS Number 606143-52-6
    SMILES CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
    Synonyms ARRY-142886
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 80 mg/mL (174.79 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.85 mL 109.24 mL 218.48 mL
    0.5 mM 4.37 mL 21.85 mL 43.7 mL
    1 mM 2.18 mL 10.92 mL 21.85 mL
    5 mM 0.44 mL 2.18 mL 4.37 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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