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| Discription | AZD6244 (Selumetinib) also known as Selumetinib, ARRY142886, AZD-6244 & ARRY-142886 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm. | |||||
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| Cell Research |
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| Catalog Num | A10257 |
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| Formula | C17H15BrClFN4O3 |
| Molecular Weight | 457.7 |
| CAS Number | 606143-52-6 |
| SMILES | CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO |
| Synonyms | ARRY-142886 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 80 mg/mL (174.79 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 4% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.85 mL | 109.24 mL | 218.48 mL |
| 0.5 mM | 4.37 mL | 21.85 mL | 43.7 mL |
| 1 mM | 2.18 mL | 10.92 mL | 21.85 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.37 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
