Azide-PEG1-Val-Cit-PABC-OH is a cleavable linker designed for use in antibody-drug conjugates (ADCs). This reagent incorporates an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. Its key application lies in the synthesis of ADCs, facilitating the precise attachment of drug components to antibodies for targeted therapy.
Azide-PEG1-Val-Cit-PABC-OH is a cleavable linker designed for use in antibody-drug conjugates (ADCs). This reagent incorporates an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. Its key application lies in the synthesis of ADCs, facilitating the precise attachment of drug components to antibodies for targeted therapy.
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