Fig. 1 · Structure
Documents & Downloads
Azide-PEG3-Desthiobiotin
PROTAC Linker
Azide-PEG3-Desthiobiotin serves as a versatile linker for PROTAC (proteolysis-targeting chimera) synthesis, facilitating targeted protein degradation. This compound features an azide functional group, enabling its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne, DBCO, or BCN-containing molecules. Its applications extend to the development of novel therapeutic agents that leverage the targeted degradation pathway for enhanced biological research and drug development.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1426828-06-9 |
| Applications | PROTAC Linker |
| Formula | C18H34N6O5 |
| Molecular Weight | 414.50 |
| SMILES | O=C(NCCOCCOCCOCCN=[N+]=[N-])CCCCC[C@H]([C@H](C)N1)NC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.