Fig. 1 · Structure
Documents & Downloads
Azide-PEG4-Tos
PROTAC Linker
Azide-PEG4-Tos is a PEG-based PROTAC linker known for facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an azide functional group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives. This compound is valuable for researchers focusing on targeted protein degradation and drug development through the innovative PROTAC technology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 168640-82-2 |
| Applications | PROTAC Linker |
| Formula | C15H23N3O6S |
| Molecular Weight | 373.42 |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.