Fig. 1 · Structure
Documents & Downloads
Azide-PEG6-Tos
PROTAC Linkers
Azide-PEG6-Tos is a PEG-based linker designed for use in the synthesis of PROTACs, targeting the PROTAC technology. This compound features an azide functional group, enabling its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized partners. Its versatility makes it a valuable tool for chemical biology research focused on targeted protein degradation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 906007-10-1 |
| Applications | PROTAC Linkers |
| Formula | C19H31N3O8S |
| Molecular Weight | 461.53 |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.