Azide-PEG8-alcohol is a polyethylene glycol (PEG)-derived linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features an azide functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties. Its versatility in click chemistry makes it a valuable tool for the development of targeted protein degradation systems in biochemical research.
Azide-PEG8-alcohol is a polyethylene glycol (PEG)-derived linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features an azide functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties. Its versatility in click chemistry makes it a valuable tool for the development of targeted protein degradation systems in biochemical research.
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