Fig. 1 · Structure

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Azide-PEG8-alcohol

PROTAC Linkers

Azide-PEG8-alcohol is a polyethylene glycol (PEG)-derived linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features an azide functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties. Its versatility in click chemistry makes it a valuable tool for the development of targeted protein degradation systems in biochemical research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 352439-36-2
Applications PROTAC Linkers
Formula C16H33N3O8
Molecular Weight 395.45
SMILES
OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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