Azido-C1-PEG3-C3-NH2 is a PEG-based linker designed for use in the synthesis of PROTACs, functioning through a click chemistry mechanism. This compound features an azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds bearing DBCO or BCN groups. Its versatility makes it valuable for research applications focused on targeted protein degradation and chemical biology.
Azido-C1-PEG3-C3-NH2 is a PEG-based linker designed for use in the synthesis of PROTACs, functioning through a click chemistry mechanism. This compound features an azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds bearing DBCO or BCN groups. Its versatility makes it valuable for research applications focused on targeted protein degradation and chemical biology.
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