Fig. 1 · Structure
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Azido-C1-PEG3-C3-NH2
PROTAC Linker
Azido-C1-PEG3-C3-NH2 is a PEG-based linker designed for use in the synthesis of PROTACs, functioning through a click chemistry mechanism. This compound features an azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds bearing DBCO or BCN groups. Its versatility makes it valuable for research applications focused on targeted protein degradation and chemical biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1162336-72-2 |
| Applications | PROTAC Linker |
| Formula | C10H22N4O3 |
| Molecular Weight | 246.31 |
| SMILES | NCCCOCCOCCOCCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.