Fig. 1 · Structure
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Azido-PEG(4)-Val-Cit-PAB-PNP
Click Chemistry Reagent
Azido-PEG(4)-Val-Cit-PAB-PNP is a versatile click chemistry reagent featuring an azide group as its primary mechanism for reaction. This compound is designed for use in peptide antibody-drug conjugates (ADCs), allowing for efficient conjugation through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its cleavable linker structure enhances the stability and bioactivity of conjugated systems, making it suitable for targeted drug delivery and research applications in bioconjugation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1869126-60-2 |
| Applications | Click Chemistry Reagent |
| Formula | C36H51N9O13 |
| Molecular Weight | 817.84 |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)COC(OC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.