Azido-PEG1-C2-acid is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound contains an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Furthermore, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing compounds, making it a versatile tool for applications in targeted protein degradation research.
Azido-PEG1-C2-acid is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound contains an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Furthermore, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing compounds, making it a versatile tool for applications in targeted protein degradation research.
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