Azido-PEG11-acid is a PEG-based linker designed for Protein-Targeting Chimera (PROTAC) synthesis. Featuring an azide functional group, it readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds and can also engage in strain-promoted azide-alkyne cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) moieties. This versatile linker is valuable for researchers focused on targeted protein degradation and therapeutic development.
Azido-PEG11-acid is a PEG-based linker designed for Protein-Targeting Chimera (PROTAC) synthesis. Featuring an azide functional group, it readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds and can also engage in strain-promoted azide-alkyne cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) moieties. This versatile linker is valuable for researchers focused on targeted protein degradation and therapeutic development.
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