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Azido-PEG11-acid

PROTAC Linkers

Azido-PEG11-acid is a PEG-based linker designed for Protein-Targeting Chimera (PROTAC) synthesis. Featuring an azide functional group, it readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds and can also engage in strain-promoted azide-alkyne cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) moieties. This versatile linker is valuable for researchers focused on targeted protein degradation and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2769916-01-8
Applications	PROTAC Linkers
Formula	C₂₅H₄₉N₃O₁₃
Molecular Weight	599.67
Synonyms	N3-PEG11-CH2CH2COOH
SMILES	OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.