Fig. 1 · Structure
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Azido-PEG2-alcohol
PROTAC Linker
Azido-PEG2-alcohol serves as a versatile PEG-based linker utilized in the design and synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing compounds. Its unique properties facilitate targeted protein degradation studies and advancements in drug development by allowing the effective conjugation of various biomolecules.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 139115-90-5 |
| Applications | PROTAC Linker |
| Formula | C4H9N3O2 |
| Molecular Weight | 131.13 |
| SMILES | [N-]=[N+]=NCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.