Azido-PEG2-C2-acid is a PEG-based linker designed for the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide functional group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. Its versatile reactivity makes it suitable for various applications in chemical biology and drug development.
Azido-PEG2-C2-acid is a PEG-based linker designed for the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide functional group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. Its versatile reactivity makes it suitable for various applications in chemical biology and drug development.
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