Fig. 1 · Structure

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Azido-PEG2-C2-acid

PROTAC Linker

Azido-PEG2-C2-acid is a PEG-based linker designed for the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide functional group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. Its versatile reactivity makes it suitable for various applications in chemical biology and drug development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1312309-63-9
Applications PROTAC Linker
Formula C7H13N3O4
Molecular Weight 203.20
SMILES
O=C(O)CCOCCOCCN=[N+]=[N-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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