Azido-PEG2-C2-Boc is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) and is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. Its application in PROTAC development allows for the effective modification of target proteins, making it a valuable tool for chemical biology research.
Azido-PEG2-C2-Boc is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) and is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. Its application in PROTAC development allows for the effective modification of target proteins, making it a valuable tool for chemical biology research.
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