Azido-PEG23-amine is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis, enabling targeted protein degradation. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool for chemical biology and drug discovery applications.
Azido-PEG23-amine is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis, enabling targeted protein degradation. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool for chemical biology and drug discovery applications.
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