Fig. 1 · Structure
Documents & Downloads
Azido-PEG24-alcohol
PROTAC Linkers
Azido-PEG24-alcohol functions as a PEG-based linker for the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. It features an azide functional group that enables click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities possessing DBCO or BCN groups. This reagent is essential for the development of targeted protein degradation strategies in biochemical research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2415674-94-9 |
| Applications | PROTAC Linkers |
| Formula | C48H97N3O24 |
| Molecular Weight | 1100.29 |
| SMILES | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.