Fig. 1 · Structure

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Azido-PEG3-alcohol

PROTAC Linker

Azido-PEG3-alcohol is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its versatile reactivity makes Azido-PEG3-alcohol a valuable tool for researchers developing targeted protein degradation systems.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 86520-52-7
Applications PROTAC Linker
Formula C6H13N3O3
Molecular Weight 175.19
SMILES
[N-]=[N+]=NCCOCCOCCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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