Azido-PEG3-aldehyde is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its azide functionality. It is suitable for use in click chemistry applications, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. In addition, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, contributing to the development of targeted protein degradation strategies in chemical biology research.
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its azide functionality. It is suitable for use in click chemistry applications, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. In addition, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, contributing to the development of targeted protein degradation strategies in chemical biology research.
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