Fig. 1 · Structure

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Azido-PEG3-aldehyde

PROTAC Linker

Azido-PEG3-aldehyde is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its azide functionality. It is suitable for use in click chemistry applications, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. In addition, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, contributing to the development of targeted protein degradation strategies in chemical biology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1807530-10-4
Applications PROTAC Linker
Formula C9H17N3O4
Molecular Weight 231.25
SMILES
O=CCCOCCOCCOCCN=[N+]=[N-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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