Fig. 1 · Structure
Documents & Downloads
Azido-PEG3-azide
PROTAC Linkers
Azido-PEG3-azide is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Azido-PEG3-azide is valuable in developing targeted protein degradation tools for biochemical research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 101187-39-7 |
| Applications | PROTAC Linkers |
| Formula | C8H16N6O3 |
| Molecular Weight | 244.25 |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.