Azido-PEG3-azide is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Azido-PEG3-azide is valuable in developing targeted protein degradation tools for biochemical research applications.
Azido-PEG3-azide is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Azido-PEG3-azide is valuable in developing targeted protein degradation tools for biochemical research applications.
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