Fig. 1 · Structure
Documents & Downloads
Azido-PEG3-NHS ester
PROTAC Linkers
Azido-PEG3-NHS ester is a PEG-based PROTAC linker featuring an azide functional group, which facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound serves as a versatile click chemistry reagent that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it ideal for targeted protein degradation studies and related applications in chemical biology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1092654-47-1 |
| Applications | PROTAC Linkers |
| Formula | C12H18N4O7 |
| Molecular Weight | 330.29 |
| SMILES | O=C(ON1C(CCC1=O)=O)COCCOCCOCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.