Azido-PEG3-phosphonic acid ethyl ester is a PEG-based linker designed for PROTAC synthesis, targeting the ubiquitin-proteasome system to facilitate protein degradation. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups, making it a valuable tool for developing targeted protein degradation strategies in chemical biology research.
Azido-PEG3-phosphonic acid ethyl ester is a PEG-based linker designed for PROTAC synthesis, targeting the ubiquitin-proteasome system to facilitate protein degradation. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups, making it a valuable tool for developing targeted protein degradation strategies in chemical biology research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
