Azido-PEG3-Val-Cit-PAB-OH is a cleavable antibody-drug conjugate (ADC) linker designed for targeted therapeutic applications. Featuring an azide functional group, it facilitates bioconjugation using copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. This versatile linker plays a crucial role in the development of ADCs, enhancing their efficacy and therapeutic index in cancer research and treatment.
Azido-PEG3-Val-Cit-PAB-OH is a cleavable antibody-drug conjugate (ADC) linker designed for targeted therapeutic applications. Featuring an azide functional group, it facilitates bioconjugation using copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. This versatile linker plays a crucial role in the development of ADCs, enhancing their efficacy and therapeutic index in cancer research and treatment.
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