Azido-PEG3-Val-Cit-PAB-PNP is a cleavable polyethylene glycol (PEG)-based linker designed for use in antibody-drug conjugates (ADCs) and PROTAC synthesis. This reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules and those with DBCO or BCN groups, respectively. Its versatile application in bioconjugation and targeted therapies makes it a valuable tool for advancing chemical biology research.
Azido-PEG3-Val-Cit-PAB-PNP is a cleavable polyethylene glycol (PEG)-based linker designed for use in antibody-drug conjugates (ADCs) and PROTAC synthesis. This reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules and those with DBCO or BCN groups, respectively. Its versatile application in bioconjugation and targeted therapies makes it a valuable tool for advancing chemical biology research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
