Fig. 1 · Structure
Documents & Downloads
Azido-PEG4-4-nitrophenyl carbonate
PROTAC Linker
Azido-PEG4-4-nitrophenyl carbonate functions as a potent linker for the creation of PROTACs, facilitating targeted protein degradation. This PEG-based compound incorporates an azide group, enabling its use in click chemistry via copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing partners. Additionally, it supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules. This reagent is valuable in chemical biology studies focused on targeted therapeutics and protein manipulation.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1422540-98-4 |
| Applications | PROTAC Linker |
| Formula | C15H20N4O8 |
| Molecular Weight | 384.34 |
| SMILES | O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCCOCCOCCOCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.