Azido-PEG4-Ala-Ala-Asn(Trt)-PAB

Catalog No.: A43454
ADC Linker
Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a cleavable linker specifically designed for antibody-drug conjugates (ADCs). This compound facilitates the conjugation of antibodies to cytotoxic drugs, enhancing targeted delivery in cancer therapy. Its unique structure allows for selective cleavage in tumor environments, leading to effective drug release and improved therapeutic efficacy. Research applications include the development of novel ADCs and the exploration of targeted delivery mechanisms in oncology research.
Grouped product items
Size Price Stock Qty
50mg
$485.00
In stock
100mg
$700.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAzido-PEG4-Ala-Ala-Asn(Trt)-PAB is a cleavable linker specifically designed for antibody-drug conjugates (ADCs). This compound facilitates the conjugation of antibodies to cytotoxic drugs, enhancing targeted delivery in cancer therapy. Its unique structure allows for selective cleavage in tumor environments, leading to effective drug release and improved therapeutic efficacy. Research applications include the development of novel ADCs and the exploration of targeted delivery mechanisms in oncology research.
Product Information
Catalog NumA43454
FormulaC47H58N8O10
Molecular Weight895.01
CAS Number2055042-67-4
SMILESO=C(C[C@H](NC([C@H](C)NC([C@H](C)NC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)=O)C(NC1=CC=C(CO)C=C1)=O)NC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2