Azido-PEG4-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It features an azide group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynyl-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with reagents containing DBCO or BCN groups. This versatility makes Azido-PEG4-azide a valuable tool for bioconjugation and targeted protein degradation studies.
Azido-PEG4-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It features an azide group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynyl-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with reagents containing DBCO or BCN groups. This versatility makes Azido-PEG4-azide a valuable tool for bioconjugation and targeted protein degradation studies.
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