Fig. 1 · Structure

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Azido-PEG4-(CH2)3OH

PROTAC Linker

Azido-PEG4-(CH2)3OH is a PEG-based linker specifically designed for the synthesis of PROTACs. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified partners, making it a versatile tool for modular drug design and protein degradation applications in chemical biology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2028281-87-8
Applications PROTAC Linker
Formula C11H23N3O5
Molecular Weight 277.32
SMILES
OCCCOCCOCCOCCOCCN=[N+]=[N-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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