Azido-PEG4-(CH2)3OH is a PEG-based linker specifically designed for the synthesis of PROTACs. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified partners, making it a versatile tool for modular drug design and protein degradation applications in chemical biology research.
Azido-PEG4-(CH2)3OH is a PEG-based linker specifically designed for the synthesis of PROTACs. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified partners, making it a versatile tool for modular drug design and protein degradation applications in chemical biology research.
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