Azido-PEG7-t-butyl ester is a PEG-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules. Additionally, Azido-PEG7-t-butyl ester can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds featuring DBCO or BCN groups, making it a versatile tool in targeted protein degradation research. Its application in the development of PROTACs facilitates the modulation of protein levels, thus advancing studies in cellular biology and therapeutic strategies.
Azido-PEG7-t-butyl ester is a PEG-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules. Additionally, Azido-PEG7-t-butyl ester can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds featuring DBCO or BCN groups, making it a versatile tool in targeted protein degradation research. Its application in the development of PROTACs facilitates the modulation of protein levels, thus advancing studies in cellular biology and therapeutic strategies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
