Azido-PEG8-C1-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds. Its versatility in click chemistry makes it an invaluable tool for researchers focused on targeted protein degradation and biochemical studies.
Azido-PEG8-C1-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds. Its versatility in click chemistry makes it an invaluable tool for researchers focused on targeted protein degradation and biochemical studies.
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