Azido-PEG8-hydrazide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. This reagent features an azide group, enabling its engagement in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can facilitate strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when paired with DBCO or BCN functionalized compounds, making it a versatile tool for bioconjugation in chemical biology research.
Azido-PEG8-hydrazide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. This reagent features an azide group, enabling its engagement in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can facilitate strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when paired with DBCO or BCN functionalized compounds, making it a versatile tool for bioconjugation in chemical biology research.
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