Azido-PEG9-Boc is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, facilitating the conjugation of alkyne- or DBCO/BCN-containing molecules, respectively. Its versatility makes Azido-PEG9-Boc a valuable tool for researchers developing targeted protein degradation strategies.
Azido-PEG9-Boc is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, facilitating the conjugation of alkyne- or DBCO/BCN-containing molecules, respectively. Its versatility makes Azido-PEG9-Boc a valuable tool for researchers developing targeted protein degradation strategies.
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